The Metabolism of γ-Aminobutyric Acid-4-C14 by Intact Rats

The metabolism of glutaric acid-3-C14 by the intact rat.

Glutaric acid has been shown to be an intermediate in the mammalian catabolism of lysine (1). Two routes have been proposed for the degradation of glutaric acid (2-5). One pathway yields acetate, and the other involves a direct conversion to the carbon chain of ac-ketoglutarate. In an effort to assess the relative importance of each pathway, we have studied the metabolism of glutaric acid-3-Cl4...

Propofol differentially inhibits the release of glutamate, γ-aminobutyric acid and glycine in the spinal dorsal horn of rats

Objective(s): Propofol (2, 6-diisopropylphenol) is an intravenous anesthetic that is commonly used for the general anesthesia. It is well known that the spinal cord is one of the working targets of general anesthesia including propofol. However, there is a lack of investigation of the effects of propofol on spinal dorsal horn which is important for the sensory transmission of nociceptive signal...

The metabolism of C14-glycerol in the intact rat.

Considerably more work has been carried out on the formation of carbohydrate from glycerol than on its incorporation into lipides. Thus, conversion of glycerol to glucose (14) and to glycogen (5-7) has been repeatedly studied in viva and in vitro (6). More recently there has been work on the incorporation of C14-glycerol carbon (8-10) and deuterioglycerol(l1) into liver glycogen. With regard to...

γ-Aminobutyric Acid Is Synthesized and Released by the Endothelium

number: 4338. 57. Grynberg A, Demaison L. Fatty acid oxidation in the heart. J Cardiovasc Pharmacol. 1996;28(suppl 1):S11–S17. 58. Thiriet M. Coronary artery disease and myocardial infarction. In: Diseases of the Cardiac Pump. Berlin: Springer; 2015:379–471.

Metabolism of Coprostanol-c14 and Cholestanol-4-c14 in Man.